Former President George W. Bush underwent a surgical procedure on Tuesday morning to insert a stent to open a blocked artery.
During the politician's annual physical examination at the Cooper Clinic in Dallas on Monday, doctors discovered a blockage in his heart and booked the procedure for the following day.
"At the recommendation of his doctors, President Bush agreed to have a stent placed to open the blockage," said George Bush's spokesman Freddy Ford.
"The procedure was performed successfully this morning, without complication, at Texas Health Presbyterian Hospital," he added.
The 67-year-old is said to be in "high spirits" and will be released from hospital on Wednesday in order to resume his normal schedule on Thursday.
Unlike his vice president, Dick Cheney who has experienced several heart problems culminating in a heart transplant in 2012, George W. Bush is known for his physical prowess.
In office for eight years (two terms), Mr Bush was an avid runner before switching to cycling following knee problems.
Since leaving the White House in 2009, George W. Bush had participated in an annual 100km bike ride through Texas with military veterans injured in Afghanistan and Iraq.