Matt and Luciana's four daughters, Alexia, 14, Isabella, 7, Gia Zavala, 5, and Stella, 2, also joined the party with the couple's A-list guests, who were rumoured to also include Brad Pitt, Angelina Jolie and George Clooney.
The celebration was held at the luxurious Sugar Beach Resort which Matt, 42, is believed to have paid a six-figure sum to rent exclusively.
The Departed actor Matt met Argentinian Luciana in 2003 while he was filming in Miami, where she worked as a bartender. Following their wedding in 2005, Matt became stepfather to Luciana's daughter from a previous marriage, Alexia, and the couple, who live in Manhattan, went on to have three more girls.
According to The Press Association a former Cabinet minister and CEO of a company that oversees St. Lucia's economic development said Matt and Luciana's lavish party would help boost the east Caribbean island's weak economy.