Matthew looked on in support when Kelly took to the stage to deliver a speech raising awareness about multiple sclerosis, the condition suffered by her brother Jack Osbourne.
"Spent all morning working on my speech for the @dosomething #awards tonight!" tweeted Kelly. "I hope it goes well I'm #nervous."
The 28-year-old need not have been worried as after the the speech was over she received a host of positive messages on Twitter from those who had been moved by her words.
CLICK ON PHOTOS FOR FULL GALLERY
Kelly chose a simple black dress with lace sleeves and black heels for the occasion. The Fashion Police presenter added a touch of colour to her outfit with her lilac hair, rep lipstick and a quirky orange handbag.
"What do you guys think of my vintage 1970's #Hermes clutch and orange ribbon to represent @racetoerasems for the @dosomething#awards tonight?" Kelly asked her Instagram followers. "It's it enough?"
Kelly, who also showed off her glittering engagement ring, was so excited by the luxury French bag that she posted another photograph of it.
"I mean really you guys this vintage #hermes is next level to me," wrote Kelly as a caption. "I bought it for my mum is Paris years ago. Im so happy to finally use it!"
The TV presenter thanked the famous mother and daughter who presented her with her silver award statue.
"Thank you so much @JoanRivers & melrivers for giving me my #DSA award tonight," tweeted Kelly. "I love you both so much!…"
Jennifer Hudson, Queen Latifah, Carmen Electra and Glee actor Matthew Morrison also attended the awards.