Her hair, her movies, her sense of humour and, of course, her love life have been an endless source of fascination for the public.
CLICK ON PHOTOS FOR FULL GALLERY
The screen beauty followed Friends with films like Along Came Polly, Marley & Me and We're The Millers. And for the last few years Jen has had a special plus one in Justin Theroux.
Take a look at this HELLO! gallery in honour of America's sweetheart.