Having been nominated by Tom Hiddleston three days ago, Benedict missed his 24-hour deadline – as a punishment, the Sherlock star was subjected to five buckets of ice-cold water.
"Bring on the bucket," he says at the start of the two-minute clip, as the water is poured over him.
But it's not over just yet and the star is doused a further four times – once in the shower, once in a suit, once on a motorbike and the final time while he's running to his car.
Making sure the social media craze maintains momentum, he goes on to nominate fellow celebrities Kylie Minogue, Lewis Hamilton and Harvey Weinstein.
The Ice Bucket Challenge is all in aid of helping to raise awareness and money in support of ALS, also known as Lou Gehrig's disease and Motor Neurone Disease, a condition that attacks the spinal cord.
Other celebrities to have taken part include Sarah Jessica Parker, David and Victoria Beckham, Rose Huntington-Whiteley, Cara Delevingne and James McAvoy.