But there is one big difference; this time round there are absolutely no vampires or werewolves in sight.
That's because the latest pictures of the British heart-throb – currently the hottest young actor on the movie circuit thanks to his role in Twilight – show him in a different light, in this upcoming romantic drama.
Remember Me stars 23-year-old Robert and Australian Lost actress Emilie de Ravin, 27, as two young lovers whose relationship is threatened by respective family tragedies.
They are joined by fellow cast-members Pierce Brosnan, who plays Robert's dad, and Oscar-winning American Beauty actor Chris Cooper.
Snippets from the trailer show the London-born talent breaking up a street fight only to find himself arrested. His father bails him out, but it's clear they have a strained relationship.
He then spots the daughter - played by Emile - of the policeman who booked him and the two begin a relationship.
It is not the first feature Rob – currently busy promoting the second instalment of the fantasy franchise, New Moon – has taken a starring part in since his breakthrough role in Twilight in 2008.
Earlier this year he was seen in Little Ashes, a Spanish-British drama film about the lives and loves of three young talents, including his character, artist Salvador Dali.