The star, who is nominated for Best Actress for her role in 12 Years A Slave, has posted several pictures of different colours and style, with the hashtag #NailDiary.
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Lupita has also made waves in the fashion industry. Jaws dropped when little-known actress Lupita Nyong'o stepped out at the Golden Globes wearing a scarlet caped Ralph Lauren dress.
The Twelve Years A Slave star's elegant, stylish appearance cemented her status as fashion's newest darling, with the industry waiting with bated breath to see what she wears to this Sunday's Oscars.
Since, she has been turning heads in a series of chic ensembles. Attending the premiere of action movie Non-Stop on Monday, the 30-year-old wore a copper-hued Lanvin ruffled creation.
And last week, she sported a burnt orange Givenchy number with a sexy plunging neckline for an awards ceremony.
Talking about the sudden interest in her style choices, Lupita said, "I wasn't the girl who bought the fashion magazines, I'd always just worn what appeals to me.
"I know that even if I don't buy the magazines and stuff, with fashion and style, you pick up influences all the time – if your eyes are open, you're being influenced by fashion and style, whether you like it or not."
She added, "I love colour and gravitate towards solid block colours. I like clean lines and a classic look, but I also like to have a sense of humour and wear things that put a smile on my face."
Lupita made an appearance at New York Fashion Week, sitting alongside Anna Wintour and Naomi Watts in the front row of the Calvin Klein show.
She wore a lilac long-sleeved Calvin Klein Collection dress with strappy heels, accessorising her ladylike dress with retro glasses and a bold lip colour.