The actor has apparently been staying on her estate in Ojai, California after leaving the home he shared with Kristen Stewart, reports People magazine.
He hasn't been seen in public since his girlfriend of four years Kristen Stewart admitted to a "momentary indiscretion" with the director of her latest film.
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Robert, 26, became friendly with Reese while filming Water for Elephants. So it makes sense that she offered her home as a retreat.
She recently told an interior design magazine: "[The house] is meditative and restorative. As soon as I drive through the gate, I relax.
"The air is fresh, the phone isn't ringing, you can't access e-mail. Time slows down."
Peace and quiet is undoubtedly what the actor needs after learning of Kristen's liaison with film maker Rupert Sanders, who is married to British Vogue model Liberty Ross, who is the mother of his two children.
The Snow White and the Huntsman director was spotted in LA on Tuesday. While London-born Rupert, 41, looked thin and preoccupied, he was still wearing his wedding ring.
He said shortly after that he hoped his wife could forgive him. "'I love (my family) with all my heart. I am praying that we can get through this together."