Lamar is "a very depressed person", said the 29-year-old as she discussed her now troubled marriage in the latest episode of Keeping Up With The Kardashians.
"There is a lot of emotional issues I think that Lamar has," Khloé explained on Sunday's episode.
"I do want to help or cater to Lamar but also there is only so much anyone can take.
"Lamar is a very depressed person, which is sad but understandable with everything that he has been through in his life."
The reality TV star gave a touching insight to their marriage at a time when their troubles were not yet made public.
"I do love Lamar with every ounce of who I am but it is really scary when someone is in such a deep low and you know they are relying on you to get them out and you are trying and trying and trying and nothing is really working."
Khloé's fertility issues were also a hot topic of discussion on the family's reality TV show, as Kim tried to get her to consider adopting a baby. It quickly became clear that the brunette feels that she is no longer in a place to consider having a baby.
Kim, who is still pregnant in the show, pressed her sister about her attempts to get pregnant and seeing a fertility doctor. She also suggested her sister see an adoption attorney.
"Why would I do that? I am not ready to continue with fertility treatment," a frustrated Khloé replied.
"There are some things that not everybody knows and me and Lamar are the only people who do need to know that.
"It is not that I am against adoption, but right now I am in a place in my life where there are a lot of moving parts," she said.
When Khloé got good news from a fertility doctor that she could carry a child, she said: "My results are good, they are positive, but I am just not at that place now to get pregnant."