Unlike many celebrities who choose to stay quiet on the subject of cosmetic surgery, Kaley told the May edition of Cosmopolitan magazine that she has never looked back on her choice to undergo the procedure, despite being so young at the time.
As Kaley's career gained momentum thanks to her starring role in sitcom 8 Simple Rules, the Californian star said she began to pay more attention to her appearance.
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"I started reading [reports] and thought, 'Maybe I need to make more of an effort and not go out in my UGGs and be disgusting,' so I started putting make-up on," she said. "And they started writing, 'Wow, someone really likes being in front of the camera', I couldn't do anything right.
"[I thought] Why am I reading this stuff?" She added. "But I'm obsessed. I openly admit to being totally insane about that."
Kaley pictured before her surgery in 2002
During the interview The Big Bang Theory actress also revealed that her whirlwind 10-day romance with superman actor Henry Cavill accelerated her profile faster than she expected.
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"I had no one following me until I met Superman," she said. "I've been in this business for 20 years and my whole life I could go anywhere, do anything, there had not been one paparazzi photo of me until like several months ago. The recognition was crazy."
Kaley married tennis player Ryan Sweeting on New Year's Eve
Kaley tied the knot with tennis player Ryan Sweeting on New Year's Eve 2013.
Kaley Cuoco and Ryan Sweeting get married
Speaking about how swiftly her wedding came around, having only started dating six months previously, Kaley said "I admit it happened fast. But that's who I am. When we met I knew he was the one."
For their wedding the couple were surrounded by around 150 guests at Hummingbird Nest Ranch in Santa Susana, California and their nuptials had a fire and ice theme.