"I am making it known that I have put an end to my shared life with Valérie Trierweiler," the French President said in a phone call to AFP news agency on Saturday.
On the same day, 48-year-old Valérie tweeted that she was leaving the Élysée Palace, the President's official residence.
"My gratitudegoes to thewonderful staffof the Élysée," she wrote. "I will never forget their dedicationoremotionat the timeof departure."
On Sunday Valérie is due to travel to India on a humanitarian mission supporting the work of French charity Action Against Hunger, while Hollande is preparing for an official visit to the USA on 11 February.
Hollande and Valérie's split follows a turbulent couple of weeks for the pair after reports emerged that the 59-year-old politician had allegedly had an affair with French actress Julie Gayet.