William, 31, will be heading to Memphis, Tennessee to attend the wedding of his close friend Guy Pelly on Saturday 3 May. Guy will be marrying his American-born bride Lizzy Wilson.
As William has been out of the country for the past month, he is planning a whistle-stop trip. The Duke of Cambridge will fly in for two days and then go straight home, according to The Mirror.
Prince William and Prince Harry are expected to attend their close friend's wedding
Prince Harry, who is often spotted enjoying nights out with Guy, is also expected to attend the club manager's nuptials.
While Kate has been a close friend of Guy's since university, the Duchess will most likely stay at home to prevent a "global media circus". The mother-of-one will no doubt want to spend quality time with her adorable nine-month-old Prince George after the family's official three-week visit overseas.
"If all three senior royals had gone it would have required a huge security detail flying to Memphis with them," an insider told the publication. "After Australia, Kate's happy to leave William and Harry to it and spend some time at home with George.
"She appreciates the media storm her attendance would cause. She's also keen to avoid overshadowing Guy and Lizzy's big day. William and Harry also don't want the thing to turn into a circus."
Kate will most likely stay at home with Prince George
Guy, who was the mastermind behind Prince William's stag do, has reportedly asked the Princes to act as ushers on his big day. Other royals who will attend include Princess Beatrice and Eugenie.
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Royal watchers will be keen to note whether Prince Harry's long-term girlfriend Cressida Bonas is invited to the wedding. The pretty blonde, 25, will most likely fly over as she has struck up a close friendship with the "down-to-earth" bride.
Bride and groom: Lizzy Wilson and Guy Pelly
The three-day wedding celebrations will kick off on Friday with drinks at the Memphis Hunt and Polo Club, close to Lizzy's family home. Guests will also have the opportunity to visit Elvis Presley's mansion nearby, where the King of Rock lived and passed away.
The main ceremony will take place on Saturday, after which guests are expected to attend the reception in fancy dress costume and party the night away. Sunday will see the extravaganza end with a lavish brunch at the club.